Table 3.

Regions of clustered allelic homozygosity

Chromosome	Band	Appoximate range (Kb)	Frequency patients (n = 70)	Frequency normals (n = 19)
1	p33-p32.3	48 700–53 300	47.7%	47.7%
1	q21.1-q21.2	145 800–148 500	49%	50%
2	q21.2-q21.3	134 334–136 693	42%	58%
3	p21.31-p21.1	46 500–52 500	71%	68%
4	p15.1	31 838–34 524	60%	57%
8	q22.2	99 200–101 200	47%	63%
8	p11.21-p11.1	41 870–43 270	49%	47%
8	q11.1-q11.21	47 040–49 000	46%	68%
10	p11.21	36 720–38 490	43%	31%
10	q22.2-q22.2	73 200–76 460	44%	31%
12	q21.32-q21.33	85 850–89 100	47%	47%
12	q24.11-q24.13	108 600–111 600	55%	68%
14	q23.3-q24.1	65 500–67 100	62%	73%
15	q12-q13.1	25 400–27 200	71%	68%
15	q15.1-q21.1	40 100–43 730	64%	84%
15	q23-q24.1	69 300–71 700	41%	15%
16	p11.2-p11.1	33 394–34 550	62%	68%
16	q11.2-q12.1	45 092–47 450	64%	63%
16	q21-q22.1	64 850–67 100	48%	57%
17	q22-q23.2	54 610–56 850	67%	68%
20	q11.22-q11.23	31 910–35 500	68%	42%

The table presents the frequency (> 40%) of clustered regions of allelic homozygosity in the patient cohort (n = 70, including in-house reference) compared to the unaffected relatives (n = 19). Kilobase range according to Genome build 19 (NCBI 37).