Table 4.
Biochemicals in nucleotide, cofactors and vitamins, and xenobiotic Pathways
| PATHWAY | SUB PATHWAY | BIOCHEMICAL NAME | KEGG | CPT1c KOCPT1c WT | Welch's Two-Samplet-Test | CAS | PUBCHEM |
|---|---|---|---|---|---|---|---|
|
Nucleotide |
Purine metabolism, (hypo)xanthine/inosine containing |
xanthine |
C00385 |
1.02 |
0.7727 |
69-89-6; |
1188 |
| hypoxanthine |
C00262 |
0.98 |
0.4343 |
68-94-0; |
790 |
||
| inosine |
|
1.00 |
0.8754 |
58-63-9; |
|
||
|
Purine metabolism, adenine containing |
adenine |
C00147 |
1.11 |
0.0801 |
73-24-5; |
190 |
|
| adenosine |
C00212 |
0.86 |
0.1407 |
58-61-7; |
60961 |
||
| N1-methyladenosine |
C02494 |
0.94 |
0.3601 |
15763-06-1; |
5460178 |
||
| adenosine 2'-monophosphate (2'-AMP) |
C00946 |
1.00 |
|
130-49-4; |
|
||
| adenosine 5'-monophosphate (AMP) |
C00020 |
0.89 |
0.2000 |
149022-20-8; |
15938965 |
||
|
Purine metabolism, guanine containing |
guanosine |
C00387 |
1.01 |
0.9130 |
118-00-3; |
6802 |
|
|
Purine metabolism, urate metabolism |
urate |
C00366 |
1.06 |
0.4983 |
69-93-2;120K5305; |
|
|
| allantoin |
C02350 |
0.76 |
0.1685 |
97-59-6; |
204 |
||
|
Pyrimidine metabolism, cytidine containing |
cytidine |
C00475 |
0.94 |
0.1562 |
65-46-3; |
6175 |
|
| cytidine 5'-monophosphate (5'-CMP) |
C00055 |
1.01 |
0.8988 |
63-37-6; |
7058165 |
||
|
Pyrimidine metabolism, orotate containing |
orotate |
C00295 |
0.86 |
0.2325 |
50887-69-9; |
967 |
|
|
Pyrimidine metabolism, uracil containing |
uracil |
C00106 |
0.97 |
0.5212 |
66-22-8; |
1174 |
|
| uridine |
C00299 |
0.91 |
0.0141 |
58-96-8; |
6029 |
||
| pseudouridine |
C02067 |
0.99 |
0.7648 |
1445-07-4; |
|
||
|
Purine and pyrimidine metabolism |
methylphosphate |
|
0.85 |
0.1460 |
7023-27-0; |
13130 |
|
|
Cofactors and vitamins |
Ascorbate and aldarate metabolism |
ascorbate (Vitamin C) |
C00072 |
0.87 |
0.1924 |
134-03-2; |
|
| dehydroascorbate |
C05422 |
1.70 |
0.2338 |
490-83-5; |
835 |
||
| threonate |
C01620 |
0.96 |
0.5529 |
70753-61-6; |
151152 |
||
|
Hemoglobin and porphyrin |
heme* |
C00032 |
0.69 |
0.3695 |
14875-96-8; |
|
|
|
Nicotinate and nicotinamide metabolism |
nicotinamide |
C00153 |
1.00 |
0.9275 |
98-92-0; |
936 |
|
| nicotinamide adenine dinucleotide (NAD+) |
C00003 |
0.87 |
0.0469 |
53-84-9; |
1,089,765,158,925,280,000 |
||
|
Pantothenate and CoA metabolism |
pantothenate |
C00864 |
0.94 |
0.7951 |
137-08-6; |
6613 |
|
| phosphopantetheine |
C01134 |
0.85 |
0.0841 |
NA; |
115254 |
||
|
Pyridoxal metabolism |
pyridoxal |
C00250 |
1.05 |
0.5803 |
65-22-5; |
1050 |
|
|
Riboflavin metabolism |
flavin adenine dinucleotide (FAD) |
C00016 |
0.93 |
0.1085 |
146-14-5;84366-81-4; |
643975 |
|
| riboflavin (Vitamin B2) |
C00255 |
0.93 |
0.2187 |
83-88-5; |
493570 |
||
| flavin mononucleotide (FMN) |
C00061 |
0.96 |
0.7167 |
130-40-5; |
710 |
||
|
Tocopherol metabolism |
alpha-tocopherol |
C02477 |
1.04 |
0.6234 |
59-02-9;10191-41-0; |
14985 |
|
| Xenobiotics |
Chemical |
glycolate (hydroxyacetate) |
C00160 |
1.06 |
0.7194 |
79-14-1; |
3,698,251,757 |
| glycerol 2-phosphate |
C02979,D01488 |
1.02 |
0.9683 |
819-83-0; |
2526 |
||
| 2-phenoxyethanol |
|
0.94 |
0.9231 |
122-99-6; |
|
||
| 2-pyrrolidinone |
|
0.84 |
0.6590 |
616-45-5; |
12025 |
||
|
Food component/Plant |
ergothioneine |
C05570 |
0.88 |
0.0968 |
58511-63-0; |
3032311 |
|
| Sugar, sugar substitute, starch | erythritol | C00503 | 0.89 | 0.0966 | 149-32-6; |