Table 5.
Genotype distribution of thePROCRpolymorphisms in CAD patients according to the outcome during follow-up
| No cardiovascular event N = 805 | Cardiovascular events N = 77 | |
|---|---|---|
| |
rs6088738 |
|
| GG |
469 (59%) |
46 (60%) |
| GA |
291 (36%) |
28 (36%) |
| AA |
40 (5%) |
3 (4%) |
| MAF(1) |
0.232 |
0.221 |
| P(2) |
p = 0.752 |
|
| |
rs6088747 |
|
| TT |
280 (35%) |
18 (24%) |
| TG |
380 (47%) |
43 (56%) |
| GG |
145 (18%) |
16 (20% |
| MAF |
0.416 |
0.487 |
| P |
p = 0.092 |
|
| |
rs867186 |
|
| AA |
639 (79%) |
62 (80%) |
| AG |
157 (20%) |
13 (17%) |
| GG |
9 (1%) |
2 (3%) |
| MAF |
0.109 |
0.110 |
| P | p = 0.948 | |
(1) MAF: Minor Allele Frequency.
(2) P-value of the Cochran-Armitage trend.
As rs2069940 and rs1415774 were in complete association with rs867186 and rs6088747, respectively, their genotype distributions were not displayed.