Table 6.
Association of the mainPROCRhaplotypes with sEPCR (log) levels in the AtheroGene study (n = 891)
|
Polymorphisms |
Haplotype Frequencies |
Haplotypic Effects* |
||||
|---|---|---|---|---|---|---|
| rs6088738 | rs6088747 | rs2069940 | rs867186 | rs1415774 | ||
| G |
T |
G |
G |
G |
0.108 |
+0.786 [0.742 - 0.829] p = 6.74 10-270 |
| G |
T |
C |
A |
G |
0.239 |
−0.027 [−0.061 - 0.007] p = 0.125 |
| G |
G |
C |
A |
A |
0.416 |
reference |
| A |
T |
C |
A |
G |
0.228 |
0.028 [−0.009 - 0.066]p = 0.143 |
| Global test for haplotypic association | χ2 with 3 df = 792.6 p =1.71 10-171 | |||||
* Additive effects of each inferred haplotype compared to the most frequent one used as the reference haplotype. Effects were adjusted for age, sex, smoking and CV events.