. 2012 Jun 8;47(12):1342–1351. doi: 10.1007/s00535-012-0600-5

Table 2.

Pharmacokinetic parameters (12.5 mg eltrombopag group, log-transformed data)

	N	n ^a	Geom. mean	95 % CI of geom. mean		SD logs	%CVb
	N	n ^a	Geom. mean	Lower	Upper	SD logs	%CVb
C _max (ng/mL)	12	11	3,413	2,549	4,570	0.4345	45.6
T _max (h)	12	11	3.44	2.459	4.823	0.5012	53.4
AUC(0–t) (ng h/mL)	12	11	65,244	46,617	91,314	0.5004	53.3
AUC(0–24) (ng h/mL)	12	11	65,236	46,748	91,035	0.4960	52.8

CI confidence interval, Geom. mean geometric mean, CVb between-subject coefficient of variance, C _max maximum plasma concentration, T _max time to maximum plasma concentration

^aOne patient was excluded from the summary statistics of pharmacokinetic parameters because the patient had used a cation-containing antacid, which affects the exposure of eltrombopag