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Selected metaanalysis of GEM-based combination chemotherapy.
| Reference | No. of pts | HR (all) | HR for platinum | HR for 5FU/capecitabine | HR for other agents |
|---|---|---|---|---|---|
| Heinemann et al. [12] | 4465 | 0.91* | 0.85 | 0.9 | 0.99 |
| Sultana et al. [13] | 9970 | 0.91 | — | — | — |
| Vaccaro et al. [14] | 2422 | 0.87 | 0.94 (cisplatin, P = 0.61) | 0.86 (P = 0.04) | — |
| 0.86 (oxaliplatin, P = 0.04) |
*ECOG PS 0-1: HR 0.76, P < 0.001; ECOG PS 2: HR 1.08, P = 0.40.
Abbreviations: HR: hazard ratio; 5FU: fluorouracil.
