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In vivo spectral fluorescence images obtained 4 days after injection of nonspecific blood pool agent, polyclonal IgG-Cy5.5 (50 μg, IV) into ATAC4 (left dorsum) (arrow) and A431 (right dorsum) (arrowhead) tumors in mice.
A (white light image) and B (Cy5.5 fluorescence image), IgG-Cy5.5 similarly accumulated in both tumors and also showed mouse body because of blood pool.
