TABLE 1.
Clinical features of the depressive illness of the affected twin including DSM-III-R A criteria reported at their worst episode
| Famno-ID | Age at interview |
Depressed mood |
Loss of interest |
Weight or appetite change |
Sleep disturbance |
Psychomotor agitation or retardation |
Fatigue/low energy |
Guilty or worthless |
Diffic. think./ conc. |
Suicidal ideation or attempt |
Onset age |
# of episodes |
Longest episode |
Impairment/ distressa |
Tx |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 46 | x | x | x | x | x | x | x | 28 | 3 | 4 years | mod/very | x | ||
| 2 | 53 | x | x | x | x | x | x | x | 22 | 2 | 5 months | mod./some what | |||
| 3 | 49 | x | x | x | x | x | x | x | x | 29 | 2 | 9 weeks | mod./very | ||
| 4 | 60 | x | x | x | x | x | x | x | x | x | 26 | 6 | 6 months | Severe/very | x |
| 5 | 47 | x | x | x | x | x | x | x | 26 | 3 | 4 months | severe/very | x | ||
| 6 | 51 | x | x | x | x | x | x | x | x | 17 | 4 | 6 weeks | severe/somewhat | x | |
| 7 | 51 | x | x | x | x | x | x | x | 22 | 6 | 4 weeks | severe/very | |||
| 8 | 55 | x | x | x | x | x | x | x | x | 27 | 2 | 1 month | severe/somewhat | ||
| 9 | 44 | x | x | x | x | x | x | x | 22 | 6 | 3 months | mod/very | |||
| 10 | 44 | x | x | x | x | x | x | x | x | 18 | 3 | 4 months | mod/very | ||
| 11 | 63 | x | x | x | x | x | x | x | x | 22 | 3 | 6 weeks | severe/very | x | |
| 12 | 55 | x | x | x | x | x | x | x | x | x | 16 | 15 | 9 Years | severe/very | x |
a
Impairment was assessed on a 3 point scale: none, moderate, severe; level of distress was assessed on a 4n point scale: none, somewhat, moderately and very distressed.