FIG. 1.

IDLV-mediated gene transfer in VSMCs. (A–B) IDLVs mediated efficient eGFP expression in VSMCs. (A) *p<0.01, ^#p<0.001 vs. IDLV-eGFP. (B) Representative micrographs at an MOI of 50. Scale bar, 100 μm. (C) IDLV-Nogo-B (at MOI of 50) facilitated Nogo-B overexpression in VSMCs (5 days post-infection) as verified by immunocytofluorescence. IDLV, integrase-deficient lentiviral vectors; VSMC, vascular smooth muscle cells; eGFP, enhanced green fluorescent protein; MOI, multiplicity of infection. Color images available online at www.liebertpub.com/hum