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IDLV-Nogo-B reduced VSMC proliferation. (A) IDLV-Nogo-B blocked VSMC proliferation, as assessed with an MTT assay at 5 days post infection. *p<0.001 vs. their LV-eGFP control and uninfected. (B) Representative micrographs (at an MOI of 50). Scale bar, 100 μm. (C) IDLV-Nogo-B did not induce VSMC apoptosis, as demonstrated using a caspase-3/7 activity assay 5 days post-transduction at an MOI of 50.
