Table 1.
Patient | Vector | MOI | Unique mappable IS | Multiple mappable IS |
---|---|---|---|---|
10 | 20 | 8 | ||
P1 | IDLV | 25 | 24 | 16 |
50 | 27 | 18 | ||
10 | 16 | 27 | ||
P2 | IDLV | 25 | 19 | 14 |
50 | 18 | 11 | ||
10 | 24 | 8 | ||
P3 | IDLV | 25 | 25 | 8 |
50 | 23 | 8 | ||
Total | 196 | 118 | ||
10 | 1972 | 169 | ||
P1 | ICLV | 25 | 1475 | 163 |
50 | 1950 | 208 | ||
10 | 1756 | 179 | ||
P2 | ICLV | 25 | 1953 | 177 |
50 | 290 | 40 | ||
10 | 778 | 91 | ||
P3 | ICLV | 25 | 578 | 59 |
50 | n.d | n.d | ||
Total | 10752 | 1086 |
MOI, multiplicity of infection; IS, integration site; IDLV, integrase-deficient lentiviral vectors; ICLV, integrase-competent lentiviral vectors; n.d, no data.