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. Author manuscript; available in PMC: 2012 Dec 17.
Published in final edited form as: Alcohol Clin Exp Res. 2009 Jul 23;33(10):1794–1805. doi: 10.1111/j.1530-0277.2009.01018.x

Figure 4. Ethanol sensitivity and rapid ethanol tolerance are altered in amnesiac and hangover mutants, respectively.

Figure 4

(A) T50 values from eRING assays with vapor from a 50% ethanol solution were lower in amnesiacChpd (amnChpd) mutants compared to ry506 control flies (*t-test, p<0.0001). (B) Development of rapid ethanol tolerance in eRING assays was significantly altered in hangoverAE10 (hangAE10) mutants compared to pZ[+] controls (*t-test, p<0.0001). Control pZ[+] flies exhibited significant rapid ethanol tolerance during a second ethanol exposure, while hangoverAE10 mutants were more sensitive to ethanol during a second exposure (individual one sample t tests, p<0.0001). Data in all panels are mean ± S.E.M for n=15 vials (25 flies/vial) from three independent experiments.