Table 1.
Clinical and biological variables by MMP-9 quartile
| Variable | MMP-9 quartile (µg/l) |
p-value (trend) |
|||
|---|---|---|---|---|---|
| Q1: < 6.1 | Q2: 6.1–9.7 | Q3: 9.8–17.1 | Q4: > 17.1 | ||
| Age, years | 45 [36, 53] | 43 [36, 52] | 43 [36, 51] | 43 [37, 51] | 0.057 |
| Men | 335 (41%) | 361 (44%) | 383 (46%) | 377 (46%) | 0.020 |
| Race / ethnicity | |||||
| Black | 384 (47%) | 369 (45%) | 420 (51%) | 527 (64%) | < 0.0001 |
| White | 240 (29%) | 270 (33%) | 256 (31%) | 209 (25%) | 0.068 |
| Hispanic | 185 (22%) | 159 (19%) | 131 (16%) | 80 (10%) | < 0.0001 |
| Hypertension | 269 (33%) | 252 (31%) | 271 (33%) | 311 (38%) | 0.013 |
| Diabetes mellitus | 93 (11%) | 92 (11%) | 87 (11%) | 115 (14%) | 0.142 |
| Metabolic syndrome | 258 (31%) | 260 (32%) | 278 (34%) | 308 (37%) | 0.006 |
| Current smoker | 155 (19%) | 180 (22%) | 258 (31%) | 370 (45%) | < 0.0001 |
| Hypercholesterolemia | 89 (11%) | 113 (14%) | 112 (14%) | 118 (14%) | 0.047 |
| Hypertriglyceridemia | 75 (9%) | 102 (12%) | 109 (13%) | 107 (13%) | 0.013 |
| Body mass index, kg/m2 | 28.5 [24.8, 33.1] | 29.3 [25.3, 34.3] | 29.6 [25.7, 35.1] | 30.5 [25.6, 35.8] | < 0.0001 |
Values shown are median [IQR], p-trend from Jonckheere–Terpstra test for continuous variables and prevalence data n (%), p-trend from Cochran Armitage test for categorical variables.