Table 3.
Hazard of Receiving Alzheimer’s disease and Alzheimer’s or other dementia Diagnosis: Hazard ratios and 95% confidence intervals in parentheses.*
| Alzheimer’s disease (n=126,650) |
Alzheimer’s/other dementia (n=126,650) |
|||
|---|---|---|---|---|
| Open-angle glaucoma |
0.91 (0.89,0.94) |
0.91 (0.88,0.93) |
0.94 (0.92,0.96) |
0.93 (0.91,0.95) |
| Male | 0.98 (0.95,1.01) |
0.97 (0.95,0.99) |
||
| Black race |
1.21 (1.16,1.26) |
1.23 (1.20,1.27) |
||
| Other race | 0.984 (0.892,1.084) |
1.026 (0.96,1.10) |
||
| Charlson comorbidity index |
1.033 (1.024,1.041) |
1.07 (1.07,1.08) |
||
| Baseline age (in years) |
1.083 (1.08,1.09) |
1.10 (1.10,1.10) |
||
| Age-related macular degeneration (AMD), dry |
1.04 (0.96,1.12) |
1.05 (0.99,1.11) |
||
| AMD, wet | 1.09 (0.98,1.22) |
1.11 (1.03,1.20) |
||
| AMD, unspecified | 1.03 (0.97,1.09) |
1.03 (0.99,1.07) |
||
| Background diabetic retinopathy |
1.20 (1.05,1.37) |
1.42 (1.30,1.55) |
||
| Proliferative diabetic retinopathy | 1.17 (0.92,1.48) |
1.59 (1.38,1.84) |
||
| Vitreous hemorrhage | 1.15 (0.95,1.39) |
1.03 (0.90,1.18) |
||
| Cataract |
1.06 (1.02,1.09) |
1.02 (1.00,1.05) |
||
| Pseudophakia/aphakia |
1.12 (1.05,1.19) |
1.13 (1.08,1.18) |
||
| Cataract surgery |
1.07 (1.03,1.11) |
1.05 (1.03,1.08) |
||
*
The hazard ratio for open-angle glaucoma is unadjusted in the first and third specifications and adjusted in the second and fourth specifications.