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. Author manuscript; available in PMC: 2013 Apr 26.
Published in final edited form as: J Med Chem. 2012 Apr 18;55(8):3725–3738. doi: 10.1021/jm201544y

Table 2.

Dark and photo cytotoxicity for Pc conjugates using the Cell Titer Blue assay.

Compound A431 cells
IC50 (µM)
Light/dark
Vero cells
IC50 (µM)
Light/dark
HEp2 cells
IC50 (µM)
Light/dark
HT-29 cells
IC50 (µM)
Light/dark
3a >100/>125 >100/>125 >100/>125 >100/>125
4b >100/>125 >100/>125 >100/>125 >100/>125
5a 15.8/>125 47.0/>125 17.0/>125 >100/>125
5b >100/>125 >100/>125 >100/>125 >100/>125
6a >100/>125 >100/>125 >100/>125 >100/>125