Table 5.

Parameter and precision estimates in the tumor growth model

Parameter	Value	RSE (%)	IIV	Shrinkage (%)
θSR (day-1)	0.063	52.3	76	5.48
θTPR (cm/day)	0.187	41.3	58	5.49
θmutation.on.SR	−0.85	9	–	–
σ	0.084	13	–	9.08

IIV inter-individual variability; RSE relative standard errors; θ _SR mean population value for shrinkage rate; θ _TPR mean population value for tumor progression rate; θ _{mutation.on.SR} mean population value for EGFR mutation on shrinkage rate; σ residual variability