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Reelin activates Cdc42 via Apoer2. A–D, GTP-bound Cdc42 was determined after 15 min of treatment with Reelin in neuronal cultures (DIV6-7) from Apoer2−/− (A), Vldlr−/− (B), Vldlr−/−, and Apoer2−/− and Vldlr−/− (double knock-out) (C), and from Dab1−/− mice (D).
