Table 4.
Cross-Trait Within-Patients/Siblings, Within-Trait Cross-Sibling and Cross-Trait Cross-Sibling Analyses
| Analysis | n | Association | β | b | P value | 95% CI: lb/ub | |
| Cross-trait within-patients analysis | 948 | HT-disorganized symptoms | −.33 | −.73 | <.001 | −.91/−.56 | |
| 946 | HT-negative symptoms | −.21 | −.51 | <.001 | −.70/−.32 | ||
| 957 | HT-positive symptoms | −.11 | −.27 | <.001 | −.46/−.07 | ||
| 880 | DFAR-disorganized symptoms | −.21 | −.12 | <.001 | −.17/−.07 | ||
| 875 | DFAR-negative symptoms | −.11 | −.07 | <.001 | −.12/−.02 | ||
| 885 | DFAR-positive symptoms | −.09 | −.05 | .008 | −.11/−.001 | ||
| Cross-trait within-siblings analysis | 1001 | HT-disorganized symptoms | −.09 | −.01 | .006 | −.02/.001 | |
| 1001 | HT-negative symptoms | −.04 | −.01 | .17 | −.04/.01 | ||
| 1001 | HT-positive symptoms | −.04 | −.01 | .22 | −.03/.01 | ||
| 935 | DFAR-disorganized symptoms | −.02 | −.0004 | .55 | −.002/.001 | ||
| 935 | DFAR-negative symptoms | −.07 | −.003 | .04 | −.01/.001 | ||
| 935 | DFAR-positive symptoms | −.02 | −.001 | .60 | −.005/.003 | ||
| Families* | |||||||
| Within-trait cross-sibling analysis | 755 | HT | .08 | <.001 | .02/.13 | ||
| 674 | DFAR | .09 | .002 | .02/.17 | |||
| 766 | IQ | .42 | <.001 | .35/.51 | |||
| Cross-trait cross-sibling analysis | 715 | HT patients-disorganized symptoms siblings | .001 | .87 | −.01/.01 | ||
| 717 | HT patients-negative symptoms siblings | .01 | .30 | −.01/.02 | |||
| 721 | HT patients-positive symptoms siblings | .002 | .75 | −.01/.02 | |||
| 640 | DFAR patients-disorganized symptoms siblings | .001 | .02 | −.0002/.003 | |||
| 639 | DFAR patients-negative symptoms siblings | .003 | .10 | −.002/.01 | |||
| 643 | DFAR patients-positive symptoms siblings | .003 | .06 | −.001/.01 | |||
Note: *All analyses are adjusted for age, gender, IQ, and the respective relevant traits (ie, social cognition in siblings and symptoms in patients); 95% CI, confidence interval for b; lb, lower bound; ub, upper bound; Abbreviations are explained in the first footnote to table 1.