Table 2.
Maternal and Paternal Hospital-Treated Infections Before, During, and After Pregnancy in a Cohort of 1 115 752 Persons Born Between 1978 and 1998, of Whom 3722 Developed Schizophrenia During 11.9 Million Person Years of Follow-Up
Mother | Father | |||||||
IRRs (95% CIs) | IRRs (95% CIs) | |||||||
Parental Infection | Cases | Incidence Ratea | Basic Modelb | Adjusted Modelc | Casesd | Incidence Ratea | Basic Modelb | Adjusted Modelc |
≥1 infection | 1234 | 4.1 | 1.43 (1.33–1.53) | 1.24 (1.16–1.33) | 794 | 4.1 | 1.29 (1.19–1.39) | 1.14 (1.05–1.23) |
No infections | 2488 | 2.8 | 1.00 (reference) | 1.00 (reference) | 2868 | 2.9 | 1.00 (reference) | 1.00 (reference) |
Note: Abbreviation is explained in the first footnote to table 1.
The incidence rate measures the number of new cases per 10 000 person years.
Adjusted for calendar year, sex, and its interaction with age.
Further adjustment for family history of psychosis.
Because of father unknown (N = 60, IRR not shown but included in the model), numbers do not add up to the total number of cases in the sample.