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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Semin Oncol. 2012 Feb;39(1):67–73. doi: 10.1053/j.seminoncol.2011.11.004

Table 1.

Differential diagnosis of monocytosis

CMML aCML JMML
Absolute monocyte count in PB > 1×109/L - > 1×109/L
% of monocyte in PB usually >=10% <10% usually >=10%
% of blast in PB/BM <20% <20% <20%
Patient age Elderly Elderly Young Children

Secondary AML derived from CMML and some primary forms of AML with monocytoid features [for example, AML with MLL translocation such as t(9;11)] have morphologic and phenotypic similarity.

CMML, chronic myelomonocytic leukemia; aCML, atypical chronic myeloid leukemia; AML, acute myeloid leukemia; JMML, juvenile myelomonocytic leukemia; PB, peripheral blood; BM, bone marrow.