Table 2.
Gene mutational status in CMML patients (cohort with >50 patients).
| Number (n) of patients |
Mutated genes |
References | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CBL | RAS | RUNX1 |
JAK2
(V617F) |
TET2 | ASXL1 | UTX | EZH2 | IDH1/2 | ||
| 63 | 14% | 11% | - | 2% | 48% | 27% | 9% | 6% | 5% | (7) |
| 81 | 19% | 27% | 9% | 10% | 51% | - | - | - | - | (21) |
| 53 | 10% | 13% | 21% | - | 36% | 49% | - | - | 10% | (25) |
| 88 | - | - | - | - | 50% | - | - | - | - | (44) |
| 69 | - | - | - | - | 42% | - | - | - | - | (41) |
| 81 | - | - | 37% | - | - | - | - | - | - | (27) |
| 78 | - | - | - | 10% | - | - | - | - | - | (30) |
| 52 | - | - | - | 13% | - | - | - | - | - | (31) |