Table 1.

Clinical scoring system for mice infected with Clostridium difficile

Category	Scores*
	0	1	2	3
Activity	normal	Alert/slow moving	Lethargic/shaky	Inactive unless prodded
Posture	normal	Back slanted	Hunched	Hunched/nose down
Coat	normal	Piloerection	Rough skin	Very ruffled/puff/ Ungroomed
Diarrhea	normal	Soft stool/discolored (yellowish)	Wet stained tail/ mucous +/- blood	Liquid/no stool (ileus)
Eyes/Nose	normal	Squinted ½ closed	Squinted/discharge	Closed/discharge

*Clinical Score=sum of all parameter scores. Total possible score=15. Normal=0; Found dead=15.