Table 3.
Comparisons of clinical and hormonal characteristics among different phenotypes of PCOS
| Parameters |
PHO |
OH |
PH |
PO |
P |
|---|---|---|---|---|---|
| (n = 50) | (n = 32) | (n = 23) | (n = 14) | (overall) | |
|
Age (year) |
22.4 ± 4.5 |
22.4 ± 4.3 |
22.3 ± 3.3 |
20.8 ± 3.4 |
NS |
|
BMI (kg/m2) |
22.6 ± 3.1 |
22.7 ± 3.2 |
22.1 ± 2.9 |
22.5 ± 4.04 |
NS |
|
WHR |
0.78 ± 0.05 |
0.77 ± 0.05 |
0.75 ± 0.06 |
0.77 ± 0.07 |
NS |
|
mFG |
8.2 ± 5.0a,* |
10.9 ± 5.1a |
10.6 ± 3.6a |
1.4 ± 1.7 |
<0.001 |
|
Testosterone (ng/dl) |
74.8 ± 37.6a |
77.9 ± 30.8a |
71.7 ± 29.1a |
35.9 ± 15.7 |
<0.001 |
|
SHBG (nmol/l) |
39.9 ± 23.5 |
36.9 ± 17.8 |
38.6 ± 20.7 |
46.0 ± 15.7 |
NS |
|
FAI |
9.9 ± 8.4a |
9.6 ± 8.0a |
8.8 ± 5.8b |
2.8 ± 1.4 |
<0.01 |
|
DHEAS (μg/dl) |
277 ± 127 b |
312 ±140b |
294 ± 136b |
174.9 ± 95.8 |
<0.01 |
|
FPG (mg/dl) |
82.0 ± 12.6 |
81.4 ± 11.5 |
83.1 ± 9.3 |
84.9 ± 14.4 |
NS |
|
Fasting insulin (μIU/ml) |
12.3 ± 7.5c |
11.2 ± 3.7c |
8.2 ± 4.1 |
10.2 ± 4.9 |
<0.01 |
| HOMA-IR | 2.6 ± 1.6c | 2.3 ± 0.8c | 1.7 ± 0.9 | 2.3 ± 1.2 | <0.05 |
Results are expressed as mean ± SD. NS not significant, PHO polycystic ovaries, oligo-anovulation and hyperandrogenism, OH oligo-anovulation and hyperandrogenism, PH polycystic ovaries and hyperandrogenism, PO polycystic ovaries and oligo-anovulation, BMI body mass index, WHR waist-to-hip ratio, mFG modified Ferriman-Gallwey score, SHBG sex hormone-binding globulin, FAI free androgen index, DHEAS dehydroepiandrosterone sulfate, FPG fasting plasma glucose, HOMA-IR homeostatic model assesment of insulin resistance.
a P <0.001 vs. PO.
b P <0.01 vs. PO.
c P <0.01 vs. PH.
*P =0.05 vs. OH.