Figure 3.

The correlation between the loss of PTEN expression and (A) histological grade or (B) AJCC stage is shown. (A) The loss of cytoplasmic PTEN expression (P= 0.016), but not nuclear or total expression, was significantly correlated with histological grade. (B) The loss of total PTEN expression was significantly correlated with AJCC stage (P= 0.012). The loss of nuclear (P= 0.013) and total (P= 0.002) PTEN expression was also significantly different between AJCC tumor stage I and stages II–IV. AJCC, American Joint Committee on Cancer.