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Diagnostic performance of conventional nested Aspergillus PCRa
| Sensitivity | Specificity | PPV | NPV | |
|---|---|---|---|---|
|
As compared to EORTC/NIAID |
|
|
|
|
| Proven |
0% |
71% |
0% |
98% |
| Proven & Probable |
36% |
72% |
7% |
95% |
| Proven & Probable & Possible |
26% |
70% |
26% |
71% |
|
As compared to clinical judgment |
|
|
|
|
| Receiving antifungal therapy |
30% |
73% |
60% |
43% |
| Suspicion of IFD on radiologic studies | 28% | 71% | 27% | 72% |
IFD = invasive fungal disease.
