Table 1.
The top 10 instances obtained from gene modularization comparison method and distance comparison method in TSA case
| A. | cMap ID | Molecule | GO counts | B. | cMap ID | Molecule |
|---|---|---|---|---|---|---|
| 1050 | trichostatin A | 56+ | 448 | trichostatin A | ||
| 1072 | trichostatin A | 55+ | 909 | HC toxin | ||
| 448 | trichostatin A | 54+ | 1072 | trichostatin A | ||
| 1014 | trichostatin A | 53+ | 1000 | vorinostat | ||
| 909 | HC toxin | 53+ | 1058 | vorinostat | ||
| 981 | trichostatin A | 52+ | 981 | trichostatin A | ||
| 1112 | trichostatin A | 50+ | 1050 | trichostatin A | ||
| 992 | trichostatin A | 50+ | 332 | trichostatin A | ||
| 331 | trichostatin A | 50+ | 331 | trichostatin A | ||
| 332 | trichostatin A | 50+ | 1112 | trichostatin A |
The top 10 instances sharing the largest number of significantly affected GOMs with TSA-treated cells are listed in A and the top 10 instances resulted from distance comparison method are listed in B.
For detailed parameter settings: BP is chosen as GO mode, and the P-value for cutting off insignificantly matched or reverse-matched GO modules is 0.05. 'plus' indicates the number of GO terms positively correlated; 'minus' indicates the number of GO terms negatively correlated.