Table 3.
The top 10 instances obtained from gene modularization comparison method and distance comparison method in Diabetes case
| A. | cMap ID | Molecule | GO counts | B. | cMap ID | Molecule |
|---|---|---|---|---|---|---|
| 1069 | 15-delta prostaglandin J2 | 63+ | 941 | rottlerin | ||
| 887 | celastrol | 54+ | 839 | 5224221 | ||
| 893 | pararosaniline | 54+ | 1069 | 15-delta prostaglandin J2 | ||
| 1011 | 15-delta prostaglandin J2 | 53+ | 978 | pyrvinium | ||
| 839 | 5224221 | 53+ | 956 | 5224221 | ||
| 956 | 5224221 | 51+ | 887 | celastrol | ||
| 941 | rottlerin | 51+ | 893 | pararosaniline | ||
| 1140 | MG-132 | 46+ | 1140 | MG-132 | ||
| 1010 | thioridazine [INN] | 45+ | 1010 | thioridazine [INN] | ||
| 976 | 5182598 | 44+ | 1011 | 15-delta prostaglandin J2 |
The top 10 instances sharing the largest number of significantly affected GOMs with adipocyte tissue fed by metformin are listed in A and the top 10 instances resulted from distance comparison method are listed in B.
Detailed parameter settings: GO mode: BP; P-value: < 0.05.