Table 1. Basal characteristics of wild-type (WT) and littermate mice with over-expression of glucose transporter 4 (G4Tg).
WT | G4Tg | |
n | 16 | 14 |
Body Weight (g) | 24±1 | 26±1 |
Blood Glucose (mg·dL−1) | 141±8 | 91±3* |
Insulin (ng·mL−1) | 0.6±0.1 | 0.6±0.1 |
Glucagon (pg·mL−1) | 41±4 | 60±10* |
NEFA (mEqL−1) | 1.7±0.3 | 1.7±0.2 |
EndoRa (mg·kg·min−1) | 17±1 | 26±2* |
Rd (mg·kg·min−1) | 17±1 | 26±2* |
Measurements were taken in 5h fasted mice prior to phloridzin-glucose clamps and represent combined data from control and experimental animals. * indicates p<0.05 compared to WT littermates.