Table 2. TCA cycle metabolism genes.

Gene ID	Fold change	Direction	adjusted p-value	Fold change qRT-PCR	Direction	p-value
Dld	1.68	Down	0.013095	2.95	Down	0.000386
Mdh1	1.64	Down	0.004434	3.29	Down	0.000167
Fh1	1.63	Down	0.006485	3.06	Down	0.001282
Idh3a	1.48	Down	0.003829	2.02	Down	0.001583
Pdha1	1.35	Down	0.00929	1.86	Down	0.003487
Sucla2	1.32	Down	0.016633	2.10	Down	0.006097
Aco1	1.28	Down	0.003759	1.34	Down	0.013955
Sdha	1.20	Down	0.010029	1.56	Down	0.015946

Genes associated with TCA cycle metabolism were identified from among the significantly differentially expressed probe sets between HFD-fed WT and Ogg1^−/− mice, using gene ontology terms in Gene Sifter. Gene expression changes were confirmed by qRT-PCR using gene-specific primers. n = 6 in each group. Idh3a, isocitrate dehydrogenase 3, Pdha1, pyruvate dehydrogenase E1 alpha 1, Sucla2, succinate-Coenzyme A ligase, Aco1, aconitase 1, Sdha, succinate dehydrogenase complex, subunit A.