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. 2012 Dec 17;7(12):e52121. doi: 10.1371/journal.pone.0052121

Table 7. Regulation of cellular assembly & organization and cell signaling-associated genes in the core and periinfarct after permanent focal cerebral ischemia.

Symbol Gene Name 24 h 3 d
Core Periinfarct Core Periinfarct
Cellular Assembly & Organization
RHOA Ras homolog gene family, member A
SMC4 Structural maintenance of chromosomes 4 3.83 (<10−9) 2.02 (<10−4)
NUF2 Kinetochore protein Nuf2 19.7 (<10−9) 7.36 (<10−5)
ECT2 ECT2 gene 3.16 (<0.05) 32.0 (<10−10) 10.6 (<10−5)
FEZ1 Fasciculation and elongation protein zeta-1 0.45 (<0.01)
TNR Tenascin-R 0.47 (<10−7)
Cell Signaling
RFTN1 Raftlin, lipid raft linker 1 2.12 (<0.01) 2.45 (<10−4) 7.06 (<10−9) 2.29 (<0.01)
NDN Necdin 0.40 (<10−5)
CCL5 Chemokine (C-C motif) ligand 5 2.39 (<0.05) 2.36 (<0.01)
CXCL1 Chemokine (C-X-C motif) ligand 1 27.1 (<0.01) 238 (<10−6) 82.7 (<10−5) 27.7 (<0.01)
CXCL10 Chemokine (C-X-C motif) ligand 10 7.36 (<10−4) 9.38 (<10−4) 6.27 (<10−4) 9.32 (<10−4)
CXCL11 Chemokine (C-X-C motif) ligand 11 11.5 (<10−4) 22.8 (<10−5) 25.3 (<10−6) 12.8 (<10−4)
CXCL12 (T1) Chemokine (C-X-C motif) ligand 12 (transcript 1)
CXCL12 (T3) Chemokine (C-X-C motif) ligand 12 (transcript 3) 0.28 (<10−9) 0.36 (<10−7)
CXCL13 Chemokine (C-X-C motif) ligand 13 4.75 (<0.05) 3.48 (<0.05) 10.9 (<10−5) 5.89 (<0.05)
CCL2 Chemokine (C-C motif) ligand 2 576 (<10−8) 560 (<10−8) 388 (<10−8) 69.1 (<10−5)
CCL4 Chemokine (C-C motif) ligand 4 15.8 (<10−7) 14.0 (<10−7) 7.94 (<10−6) 2.88 (<0.05)
CCL5 Chemokine (C-C motif) ligand 5 2.39 (<0.05) 2.36 (<0.01)
CCL20 Chemokine (C-C motif) ligand 20 46.2 (<10−5) 90,5 (<10−6) 4.86 (<0.05)
MyD88 Myeloid differentiation primary response gene 88 2.27 (<0.01) 2.00 (<0.05) 2.71 (<10−4)
ANGPT2 Angiopoietin-2 3.41 (<0.05) 2.92 (<0.05) 2.36 (<0.05)
CALCB Calcitonin-related polypeptide beta 18.4 (<10−8) 12.2 (<10−6) 61.8(<10−11) 11.8 (<10−6)

Expression is given by fold change in value compared with healthy controls. Adjusted p-value (AdjP) is given in parenthesis.