Table I.
Counts of mitotic and PCNA-positive cells in Colon26 tumor sections.
| Variable | Mitosis (/HPF) | PCNA (%) |
|---|---|---|
| Vehicle control (CD) | 19.1±1.6 | 77.0±1.4 |
| CD-MGDG complex (MGDG 4 mg/kg eq.) | 14.7±1.5 | 67.3±2.2a |
| CD-MGDG complex (MGDG 20 mg/kg eq.) | 11.7±1.3a | 59.4±2.5a |
Mice were orally treated with CD (200 mg/kg), CD (40 mg/kg)-MGDG (4 mg/kg) complex or CD (200 mg/kg)-MGDG (20 mg/kg) complex. Histopathological analysis was performed at a HPF (×400). Data are expressed as the mean ± SE.
a
Significantly different from the control (P<0.05). CD, γ-cyclodextrin; MGDG, monogalactosyl diacylglycerol; HPF, high power field; PCNA, proliferating cell nuclear antigen.