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. 2012 Dec 17;7(12):e51635. doi: 10.1371/journal.pone.0051635

Table 1. Showing the results of ANCOVA–analysis according to FTO genotype.

FTO SNP rs8050136 (N = 773)
Genotype CC CA AA
N = 269 N = 380 N = 124
35% 49% 16%
BMI (kg· m 2 ) 24.5±3.6 24.8±3.7 25.7±4.3*
Waist circumference (cm) 85.8±10.3 86.0±9.7 88.8±12.2#
Fat per cent (%) 17.5±7.2 17.9±7.0 19.4±8.0
VO2max (mL·kg 1 ·min 1 ) 42.0±8.3 41.8±7.8 40.2±8.6
VO2max (L·min 1 ) 3.29±0.56 3.30±0.58 3.30±0.62
Maximal working capacity (Watts) 244.2±44.7 245.0±46.5 242.7±49.1
Maximal force of leg extensors (N) 2927±872 2950±816 2942±992
Plasma leptin (pg·mL −1 ) 3598±3657 3702±3780 4289±4278

Earlier physical activity, smoking and age were set as covariates. Bonferroni correction was accounted for multiple post-hoc comparisons.

BMI: p = 0.007 for main effect, *p = 0.005 between the genotype groups CC and AA.

Waist circumference: p = 0.012 for main effect, #p = 0.012 between the genotype groups CC and AA.

p>0.0125 for main effect between genotype groups for rest of the variables.