Table 1. Showing the results of ANCOVA–analysis according to FTO genotype.
FTO SNP rs8050136 (N = 773) | |||
Genotype | CC | CA | AA |
N = 269 | N = 380 | N = 124 | |
35% | 49% | 16% | |
BMI (kg· m −2 ) | 24.5±3.6 | 24.8±3.7 | 25.7±4.3* |
Waist circumference (cm) | 85.8±10.3 | 86.0±9.7 | 88.8±12.2# |
Fat per cent (%) | 17.5±7.2 | 17.9±7.0 | 19.4±8.0 |
VO2max (mL·kg −1 ·min −1 ) | 42.0±8.3 | 41.8±7.8 | 40.2±8.6 |
VO2max (L·min −1 ) | 3.29±0.56 | 3.30±0.58 | 3.30±0.62 |
Maximal working capacity (Watts) | 244.2±44.7 | 245.0±46.5 | 242.7±49.1 |
Maximal force of leg extensors (N) | 2927±872 | 2950±816 | 2942±992 |
Plasma leptin (pg·mL −1 ) | 3598±3657 | 3702±3780 | 4289±4278 |
Earlier physical activity, smoking and age were set as covariates. Bonferroni correction was accounted for multiple post-hoc comparisons.
BMI: p = 0.007 for main effect, *p = 0.005 between the genotype groups CC and AA.
Waist circumference: p = 0.012 for main effect, #p = 0.012 between the genotype groups CC and AA.
p>0.0125 for main effect between genotype groups for rest of the variables.