Table 1. Top SNPs (p-value <1.25E-7) from GWAS of Alzheimer disease, fibrinogen, HDL and uric acid using 550K genotype data.

Trait	SNP	Chr	Position†	ClosestRefGene	HWE p	callrate	MAF*	N	beta	se	p
Alzheimer disease	rs4420638††	19	50114786	APOC1	0.78	0.999	0.16	3192	0.856	0.124	5.96E-12
Fibrinogen	rs4681	4	155710282	FGB	0.53	0.998	0.18	7271	10.009	1.446	4.48E-12
HDL	rs3764261	16	55550825	CETP	0.04	0.982	0.31	7996	3.077	0.266	5.71E-31
	rs1919484	8	19913956	LPL	0.11	0.981	0.27	7999	1.948	0.276	1.76E-12
	rs10186236	2	115096721	DPP10	0.21	0.999	0.19	8128	−1.647	0.307	7.79E-8
	rs1800588	15	56510967	LIPC	0.65	1.000	0.22	8134	1.514	0.293	2.42E-7
Uric acid	rs16890979	4	9531265	SLC2A9	0.01	0.998	0.25	8229	−0.352	0.022	2.64E-59
	rs2231142	4	89271347	ABCG2	0.76	0.999	0.11	8234	0.246	0.031	1.46E-15
	rs1165205	6	25978521	SLC17A3	0.19	0.985	0.46	8096	−0.105	0.019	4.34E-8

^†Position in base pairs, based on NCBI build 36.1 (hg18).

^*MAF is computed in genotyped and phenotyped sample.

^††rs4420638 is a marker of the APOE haplotype.