Table IV.
Complementary value of GGT-II, AFU and AFP to diagnose hepatocellular carcinoma.
| Markers | Sensitivity (%) | Specificity (%) | Accuracy (%) |
|---|---|---|---|
| Positive GGT-II (a) | 84.1 (95/113)a | 95.1 (97/102)d | 89.3 (192/215) |
| Positive AFU (b) | 56.9 (64/113)b | 82.4 (84/102)e | 68.8 (148/215) |
| Positive AFP (c) | 59.3 (67/113)b | 81.4 (83/102)e | 69.8 (150/215) |
| a+b | 92.9 (105/113) | 78.4 (80/102)f | 86.0 (185/215) |
| a+c | 93.8 (106/113) | 77.5 (79/102)f | 86.0 (185/215) |
| b+c | 83.2 (94/113)c | 68.8 (70/102) | 76.3 (164/215) |
| a+b+c | 97.3 (110/113) | 64.7 (66/102) | 81.9 (176/215) |
a
P<0.05, a vs. b, c, (a+b), (a+c) and (a+b+c);
b
P<0.05, b and c vs. (a+b), (a+c), (b+c) and (a+b+c);
c
P<0.05, (b+c) vs. (a+b), (a+c) and (a+b+c);
d
P<0.05, a vs. other groups;
e
P<0.05, b and c vs. (b+c) and (a+b+c);
f
P<0.05, (a+b) and (a+c) vs. (a+b+c). Statistical analyses were performed using Chi-square or Fisher’s exact tests. GGT-II, γ-glutamyl transferase isoenzyme II; AFU, α-L-fucosidase; AFP, α-fetoprotein.