Table 3.
Treatment | New-Onset AF (n=3112) |
P Value (New vs. No) |
Pre-existing AF (n=4494) |
P Value (Pre vs. No) |
No AF (n=51,426) |
P Value (New vs. Pre) |
---|---|---|---|---|---|---|
In-Hospital Medications | ||||||
Aspirin | 2902 (93.3%) | 0.05 | 3849 (86.0%) | <0.001 | 48377 (94.2%) | <0.001 |
Beta-blocker | 2458 (79.5%) | <0.001 | 3390 (76.0%) | <0.001 | 43808 (85.7%) | <0.001 |
ACE inhibitor | 2207 (71.6%) | <0.001 | 2837 (63.7%) | 0.0024 | 33672 (65.9%) | <0.001 |
Statin | 1905 (61.8%) | <0.001 | 2645 (59.3%) | <0.001 | 36270 (80.0%) | 0.031 |
Clopidogrel | 1074 (52.6%) | <0.001 | 1300 (43.4%) | <0.001 | 21371 (61.1%) | <0.001 |
Amiodarone | 1554 (50.5%) | <0.001 | 1067 (24.1%) | <0.001 | 2318 (4.6%) | <0.001 |
Low molecular weight heparin | 1870 (60.9%) | 0.43 | 2402 (54.1%) | <0.001 | 30614 (60.2%) | <0.001 |
Unfractionated heparin | 1746 (56.9%) | <0.001 | 1834 (41.4%) | <0.001 | 23248 (45.8%) | <0.001 |
Warfarin | 556 (18.2%) | <0.001 | 1317 (29.7%) | <0.001 | 1768 (3.5%) | <0.001 |
GpIIbIIIa Inhibitor | 845 (27.6%) | 0.65 | 728 (16.4%) | <0.001 | 14185 (27.9%) | <0.001 |
Procedures | ||||||
PCI | 1011 (32.6%) | <0.001 | 1010 (22.6%) | <0.001 | 21036 (41.2%) | <0.001 |
Thrombolytics | 460 (15.0%) | 0.0499 | 229 (5.2%) | <0.001 | 6985 (13.7%) | <0.001 |
CABG | 587 (19.0%) | <0.001 | 133 (3.0%) | <0.001 | 2306 (4.5%) | <0.001 |
IABP | 337 (11.1%) | <0.001 | 80 (1.8%) | 0.03 | 1173 (2.3%) | <0.001 |
Permanent Pacemaker | 343 (11.3%) | <0.001 | 200 (4.5%) | <0.001 | 1250 (2.5%) | <0.001 |
Discharge Prescription | ||||||
Aspirin | 2121 (87.4%) | <0.001 | 2897 (79.7%) | <0.001 | 40338 (92.1%) | <0.001 |
Beta-blocker | 1725 (71.3%) | <0.001 | 2593 (71.4%) | <0.001 | 35180 (80.6%) | 0.93 |
ACE inhibitor | 1565 (65.0%) | 0.14 | 2235 (61.7%) | 0.03 | 27675 (63.5%) | 0.01 |
Statin | 1529 (63.3%) | <0.001 | 2268 (62.6%) | <0.001 | 32221 (73.9%) | 0.57 |
Clopidogrel | 649 (40.9%) | <0.001 | 893 (36.7%) | <0.001 | 16659 (56.1%) | 0.008 |
Warfarin | 476 (20.0%) | <0.001 | 1254 (34.7%) | <0.001 | 1632 (3.8%) | <0.001 |
ACE = Angiotensin converting enzyme; PCI = Percutaneous intervention; CABG = coronary artery bypass surgery; IABP = intraaortic balloon pump