Influence of NMDA (Panel A) (10−8, 10−6 M) and hypotension (Panel B) (moderate, severe) on pial artery diameter before (control) and 1h after FPI in vehicle, glucagon (25 μg/kg iv), glucagon + PAI-1DP, glucagon + SP 600125, glucagon + U 0126, PAI-1DP, SP 600125, and U 0126 (all 1 mg/kg iv) post-injury treated animals, n=5. *p<0.05 compared with corresponding Control value +p<0.05 compared with corresponding FPI vehicle treated value.