Figure 5.

Dp53 and DΔNp53 differentially regulated wg expression. (a–d) Overexpression of Dp53 or DΔNp53 in p53 mutant flies. Dp53 (a and c) (MS1096>Dp53; p53^−/−) and DΔNp53 (b and d) (MS1096>DΔNp53; p53^−/−) are expressed in p53 mutant wing imaginal discs. (a and b) Overproduction of Dp53 or DΔNp53 leads to strong active caspase 3 staining (green). (c and c′) The overproduction of Dp53 inhibits wg expression at the dorso-ventral boundary (arrow). (d and d′) The overproduction of DΔNp53 induces wg expression (arrow). c′ and d′ are magnified views of the rectangles shown in c and d, respectively. Scale bars are 100 μm