Oxygen pressure (A) and 8-isoprostane level (B) changes up to 24 h postoperatively in the hyperoxic/standard compared with the controlled reoxygenation cardiopulmonary bypass (CPB) groups. Time 1, preoperatively; time 2, X-clamp off; time 3, 30 min X-clamp off; time 4, 2 h X-clamp off; time 5, 6 h X-clamp off; time 6, 24 h X-clamp off. **P < 0.01 and *P < 0.05 vs. time 1 in the Hyperoxic/Standard group.