Table 1.
Baseline patients' characteristics and clinical outcomes
| Controlled Reoxygenation (n = 24) | Hyperoxic/Standard (n = 25) | P Value | |
|---|---|---|---|
| Age, mo | 10.5 ± 9.9 | 11.5 ± 6.5 | 0.1 |
| Weight, kg | 8.4 ± 2.3 | 8.2 ± 2.3 | 0.7 |
| Preoperative saturations, % | 80.3 ± 9.1 | 81.7 ± 5.9 | 0.5 |
| Echo RV wall thickness, mm | 6.5 ± 0.5 | 6.9 ± 0.7 | 0.2 |
| Echo RV wall indexed, mm/m2 | 15.8 ± 3.6 | 17.3 ± 3.7 | 0.4 |
| Echo VSD size, mm | 11.5 ± 3.0 | 10.3 ± 1.3 | 0.2 |
| CPB time, min | 107.4 ± 30.3 | 109.6 ± 29.9 | 0.4 |
| Cross-clamp time, min | 61.7 ± 19.6 | 68.7 ± 15.3 | 0.1 |
| Ventilation time, h | 21.4 (21.7–50.2) | 32.0 (30.1–73.2) | 0.03 |
| Dopamine support duration, h | 24.0 (20.9–38.6) | 37.0 (30.8–73.8) | 0.05 |
| Hospital stay, days | 7.5 (6.7–15.8) | 8.0 (6.9–17.8) | 0.2 |
| Lactate, mcg/l | >0.5 | ||
| T1 = preoperatively | 1.13 ± 0.3 | 1.03 ± 0.4 | |
| T2 = X-clamp off | 1.13 ± 0.3 | 1.04 ± 0.3 | |
| T3 = 30 min X-clamp off | 1.17 ± 0.4 | 1.05 ± 0.3 | |
| T4 = 2 h X-clamp off | 1.19 ± 0.4 | 1.57 ± 0.8* | |
| T5 = 6 h X-clamp off | 1.28 ± 0.9 | 1.09 ± 0.4 | |
| T6 = 24 h X-clamp off | 1.24 ± 0.4 | 1.28 ± 0.6 |
Data are means ± SD or median and interquartile range. RV, right ventricle; X-clamp, aortic cross clamp (cardioplegic ischemic time). *P < 0.05 vs. T1, T2, and T3 in the Hyperoxic/Standard group.