Table 4.
Genes exhibiting 1.6-fold or greater expression change in ventricular biopsy of post-op hyperoxic vs. postop controlled reoxygenation patients
| Gene | Symbol | NCBI Gene ID | Fold in Hyperoxic | P Value |
|---|---|---|---|---|
| Deiodinase, iodothyronine, type II | DIO2 | 1734 | 1.900 up | 0.0235 |
| Phosphodiesterase 1A, calmodulin-dependent | PDE1A | 5136 | 1.813 up | 0.00774 |
| Actin, alpha 1, skeletal muscle | ACTA1 | 58 | 1.755 up | 0.0168 |
| MOCO sulphurase C-terminal domain containing 1 | MOSC1 | 64757 | 1.740 up | 0.0168 |
| Cysteine-rich protein 3 | CRIP3 | 401262 | 1.700 up | 0.00171 |
| GABA(A) receptor-associated protein like 1 | GABARAPL1 | 23710 | 1.612 up | 0.0123 |
| CDNA FLJ38472 fis, clone FEBRA2022148 | 3.167 down | 0.00935 | ||
| CDNA FLJ40901 fis, clone UTERU2003704 | 2.658 down | 0.00731 | ||
| Branched chain aminotransferase 1, cytosolic | BCAT1 | 586 | 2.644 down | 0.0105 |
| CDNA FLJ38472 fis, clone FEBRA2022148 | 2.512 down | 0.00654 | ||
| Versican | VCAN | 1462 | 2.365 down | 0.0106 |
| Mesoderm specific transcript homolog | MEST | 4232 | 2.135 down | 0.00819 |
| GULP, engulfment adaptor PTB domain containing 1 | GULP1 | 51454 | 2.031 down | 0.0121 |
| Inturned planar cell polarity effector homolog | INTU | 27152 | 2.017 down | 0.0157 |
| Solute carrier family 25, member 30 | SLC25A30 | 253512 | 1.982 down | 0.00218 |
| Neuroligin 4, X-linked | NLGN4X | 57502 | 1.954 down | 0.00423 |
| Hypothetical protein LOC728555 /// hypothetical protein LOC730391 | LOC728555 /// LOC730391 | 728555 /// 730391 | 1.927 down | 0.0194 |
| Ras homolog gene family, member U | RHOU | 58480 | 1.895 down | 0.0165 |
| Neurotrimin | HNT | 50863 | 1.876 down | 0.0123 |
| Vacuolar protein sorting 35 homolog | VPS35 | 55737 | 1.853 down | 0.0217 |
| TIA1 cytotoxic granule-associated RNA binding protein | TIA1 | 7072 | 1.791 down | 0.0127 |
| Glycoprotein M6B | GPM6B | 2824 | 1.789 down | 0.0137 |
| Collagen, type I, alpha 2 | COL1A2 | 1278 | 1.782 down | 0.00884 |
| Insulin-degrading enzyme | IDE | 3416 | 1.755 down | 0.00773 |
| Calcitonin receptor-like | CALCRL | 10203 | 1.747 down | 0.00625 |
| Asparagine-linked glycosylation 13 homolog | ALG13 | 55849 | 1.745 down | 0.00513 |
| Ankyrin 3, node of Ranvier (ankyrin G) | ANK3 | 288 | 1.735 down | 0.0205 |
| ATG10 autophagy related 10 homolog | ATG10 | 83734 | 1.722 down | 0.00197 |
| Fer-1-like 3, myoferlin | FER1L3 | 26509 | 1.719 down | 0.00849 |
| Ubiquitin-like modifier activating enzyme 6 | UBA6 | 55236 | 1.708 down | 0.0172 |
| Solute carrier family 30 (zinc transporter), member 7 | SLC30A7 | 148867 | 1.707 down | 0.00933 |
| Quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating)) | QPRT | 23475 | 1.706 down | 0.0212 |
| CDNA clone IMAGE:5270438 | 1.698 down | 0.00574 | ||
| Solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 | SLC35D1 | 23169 | 1.697 down | 0.021 |
| Tetratricopeptide repeat domain 3 | TTC3 | 7267 | 1.697 down | 0.0118 |
| Zinc finger, SWIM-type containing 7 | ZSWIM7 | 125150 | 1.692 down | 0.0242 |
| Ectonucleoside triphosphate diphosphohydrolase 1 | ENTPD1 | 953 | 1.691 down | 0.0123 |
| Zinc finger protein 302 | ZNF302 | 55900 | 1.684 down | 0.0233 |
| Tau tubulin kinase 2 | TTBK2 | 146057 | 1.682 down | 0.0199 |
| Kruppel-like factor 9 | KLF9 | 687 | 1.679 down | 0.0201 |
| Family with sequence similarity 114, member A1 | FAM114A1 | 92689 | 1.678 down | 0.000927 |
| KIAA1199 | KIAA1199 | 57214 | 1.670 down | 0.0113 |
| Cdc2-related kinase, arginine/serine-rich | CRKRS | 51755 | 1.667 down | 0.00753 |
| Zinc finger protein 397 | ZNF397 | 84307 | 1.659 down | 0.0207 |
| Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | SLC6A6 | 6533 | 1.658 down | 0.015 |
| Transcribed locus | 1.655 down | 0.0101 | ||
| Pleckstrin homology domain interacting protein | PHIP | 55023 | 1.654 down | 0.0156 |
| Interleukin 1 receptor-like 1 | IL1RL1 | 9173 | 1.652 down | 0.0112 |
| 1.648 down | 0.00417 | |||
| Cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) pseudogene | CMAH | 8418 | 1.646 down | 0.00472 |
| CDNA FLJ36491 fis, clone THYMU2018197 | 1.645 down | 0.0147 | ||
| NIMA (never in mitosis gene a)-related kinase 3 | NEK3 | 4752 | 1.638 down | 0.00289 |
| CDNA FLJ39389 fis, clone PLACE6003621 | 1.631 down | 0.00536 | ||
| Jun oncogene | JUN | 3725 | 1.630 down | 0.016 |
| Neuroblastoma RAS viral (v-ras) oncogene homolog | NRAS | 4893 | 1.621 down | 0.0189 |
| Aldehyde dehydrogenase 1 family, member A2 | ALDH1A2 | 8854 | 1.619 down | 0.00912 |
| Zinc finger protein 347 | ZNF347 | 84671 | 1.618 down | 0.00557 |
| Ankyrin repeat and SOCS box-containing 15 | ASB15 | 142685 | 1.617 down | 0.00804 |
| Brain expressed X-linked 2 | BEX2 | 84707 | 1.600 down | 0.0198 |