Table 1.
Dynamic of the skin ulcer state according to received therapy (Case 3).
| Data | 29.08.06 | 6.9.06 | 19.9.06 | 28.9.06 | 14.11.06 | 30.11.06 | 10.1.07 | 1.2.07 | 17.4.07 |
|---|---|---|---|---|---|---|---|---|---|
| Day of therapy | 17 | 25 | 38 | 47 | 92 | 108 | 148 | 169 | 246 |
| Therapy | AAVAA+ Cyc+PSMP IVIG+PR | AAVAA +PR | AAVAA+Cyc +PSMP IVIG +CyA+PR | AAVAA +CyA+PR | Cyc +PSMP +CyA +PR | Cyc +PSMP +CyA +PR | AAVAA +Cyc +PSMP IVIG +Rem PR | AAVAA +Cyc +PSMP IVIG +Rem PR | AAVAA +Cyc +PSMP IVIG +Rem +PR |
| State of skin ulcer | Start of gran, crusts, no discharge | Start of gran, crusts, no discharge | Gran, crusts, partial ulcer healing | Gran, crusts, partial ulcer healing | Complete ulcer healing | Complete ulcer healing | Ulcer relapse Neuropathy | Ulcer gran, crusts | Ulcer healing, hyperpygmentation |
AAVAA – aseptic, antibiotic, vascular, anticoagulant, antiaggregant complex; Cyc – cyclophosphamide; PSMP – puls methylprednisolone; IVIG – intravenous immunoglobulines; Rem – Remicade (Infliximab); PR – prednisone; gran – granulations.