Schematic structures of the Tr4 polymer end groups. Six derivatives of polymer Tr4 were synthesized via copper-catalyzed 1,3-dipolar cycloaddition that yielded different end functionalization. Polymer Tr4 was capped with the following structures: (A) adamantane, (B) carboxy, (C) alkynyl-oligoethyleneamine, (D) azido trehalose, (E) octyl, and (F) oligoethylenamine.