Table 3. Predictors of treatment failure among patients in studies conducted under India’s National Antimalarial Drug Resistance Monitoring System, India, 2009–2010.
| Predictor | RRa (95% CI) |
|---|---|
| Artesunate dose (mg/kg)b | |
| ≥ 3.5 | – |
| 3.0 to < 3.5 | 2.45 (0.58–10.3) |
| < 3.0 | 6.10 (1.04–35.8) |
| Age (years) | |
| < 5 | 4.46 (1.35–14.7) |
| ≥ 5 | – |
| Parasitaemia (asexual parasites/μl) | |
| ≥ 5 000 | 0.47 (0.22–1.00) |
| < 5 000 | – |
| Fever at enrolment (≥ 37.5 °C) | |
| Yes | 3.94 (1.40–11.1) |
| No | – |
RR, relative risk; CI, confidence interval.
a Relative risk for the failure of treatment of Plasmodium falciparum infection with a combination of artesunate and sulfadoxine-pyrimethamine, as estimated in a multivariate analysis.
b The dose given per day.