Table 1.

Examples of diseases caused by non-allelic HR.

Disease	Inheritance	Type of NAHR	Size	OMIM
Velocardiofacial syndrome	Autosomal dominant	Deletion	3 Mb	192430
Haemophilia A	X-linked recessive	Inversion	500 kb	306700
Charcot-Marie-Tooth type 1A	Autosomal dominant	Duplication	1.5 Mb	118220
AZFa	Y-linked	Deletion	800 kb	400042
Congenital adrenal hyperplasia	Autosomal recessive	Gene conversion	N/A	201910
Gaucher disease	Autosomal recessive	Gene conversion	N/A	230800
Hunter syndrome	X-linked recessive	Inversion	20 kb	309900
Prader-Willi Syndrome	Autosomal dominant	Deletion	3.5 Mb	176270
Alpha-thalassaemia	Autosomal recessive	Deletion	3.7 kb*	141800

NAHR, non-allelic homologous recombination; OMIM, database of online Mendelian inheritance in Man; Mb, megabases; kb, kilobases.

* There are alpha-globin deletions of varying sizes, this is one of the smallest.