Table 1.
| |||
---|---|---|---|
Entry | Base | Solvent | Result[a] |
1 | LiHMDS | DMF | trace |
2 | LiHMDS | Et2O | N.R. |
3 | LiHMDS | THF | 23 |
4 | LiHMDS | 1,4-Dioxane | N.R. |
5 | LiOiPr | THF | N.R. |
6 | LiOiPr | 1,4-Dioxane | N.R. |
7 | NaHMDS | THF | 40% |
8 | NaHMDS | Et2O | 75% |
9 | NaHMDS | 1,4-Dioxane | 96% |
10 | KOtBu | THF | decomp |
11 | KOtBu | 1,4-Dioxane | decomp |
GC yields, using pentadecane as an internal standard.