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. Author manuscript; available in PMC: 2013 Jan 27.
Published in final edited form as: Angew Chem Int Ed Engl. 2011 Dec 15;51(5):1225–1227. doi: 10.1002/anie.201106969

Table 3.

Synthesis of Polyfluoroaryl Oxiranes.

graphic file with name nihms416173u3.jpg
Entry Ketone 1 Bromide 3 Product 2 Yield, %[a] (dr)
1 1a 3b 2n graphic file with name nihms416173t27.jpg 80
2 1a 3c 2o graphic file with name nihms416173t28.jpg 84
3 1a 3d 2p graphic file with name nihms416173t29.jpg 60
4 1l 3b 2q graphic file with name nihms416173t30.jpg 86 (85:15)
5 1m 3b 2r graphic file with name nihms416173t31.jpg 81 (77:23)
6 1m 3c 2s graphic file with name nihms416173t32.jpg 75 (90:10)
7 1m 3d 2t graphic file with name nihms416173t33.jpg 77 (90:10)
[a]

Isolated yields of 0.5 mmol reactions.