Table 1.
Type | Annotations |
---|---|
Mapping and sequence | Chromosome bands; GC percent; CpG Islands; restriction enzyme recognition sites; BAC and fosmid clones; STS markers from genetic, RH maps; Mitelman breakpoints |
Genes, transcription and expression | RefSeq mRNAs; VEGA genes; Ensembl genes; UniGene; pseudogenes; retroposed genes; Non-coding RNA genes; tRNAs; mRNAs and ESTs; computational gene predictions; GNF Atlas expression values; Affymetrix microarray probes; DNase1 hypersensitive sites |
Variation and repeats | SNPs from dbSNP, HapMap projects haplotypes; recombination rates and hotspots; segmental duplications; repetitive sequences (RepeatMasker); tandem repeats |
Cross-species | Evolutionarily conserved regions; syntenic mappings to many organisms including chimp, mouse, rat, chicken, cow, dog, opossum, fish |
Abbreviations: BAC, bacterial artificial chromosome; EST, expressed sequence tag; GNF, Genomics Institute of the Novartis Research Foundation; NCBI, National Center for Biotechnology Information; RH, Radiation hybrid; SNP, single nucleotide polymorphism; STS, sequence-tagged site; UCSC, University of California Santa Cruz; VEGA, Vertebrate Genome Annotation.