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. 2008 Sep 1;3(1):36–52. doi: 10.1186/1479-7364-3-1-36

Supplementary Table.

Included association studies stratified by locus

Study locus std N a1/a1 a1/a2 a2/a2 N p-value
Brummett 5-HTTLPR 47.62162 33 91 78 202 0.4612
Comings 5-HTTLPR 47.72973 58 95 51 204 0.3294
Du 5-HTTLPR 46.75676 40 86 60 186 0.3763
Ebstein 5-HTTLPR 43.24324 32 66 23 121 0.3611
Flory 5-HTTLPR 48.86486 37 112 76 225 0.7835
Greenberg 5-HTTLPR 58.16216 66 217 114 397 0.0328
Gusatavsson 5-HTTLPR 46.16216 35 83 57 175 0.6461
Gusatavsson 5-HTTLPR 43.45946 22 66 37 125 0.4725
Hamer 5-HTTLPR 70.97297 108 336 190 634 0.053
Herbst 5-HTTLPR 59.67568 79 198 148 425 0.3712
Hu 5-HTTLPR 77.72973 135 390 234 759 0.2373
Jorm 5-HTTLPR 77.72973 155 350 254 759 0.0896
Katsuragi 5-HTTLPR 42.16216 66 31 4 101 1
Kumakiri-TCI 5-HTTLPR 44.48649 85 48 11 144 0.26
Lang 5-HTTLPR 49.02703 41 102 85 228 0.2748
Lesch 5-HTTLR 52.05405 52 141 91 284 0.9039
Lesch 5-HTTLPR 48.64865 43 106 72 221 0.7841
Mazzanti 5-HTTLPR 48.32432 41 106 68 215 1
Melke 5-HTTLPR 46.97297 35 84 71 190 0.2915
Murakami 5-HTTLPR 46.91892 124 55 10 189 0.2523
Nakamura 5-HTTLPR 46.75676 128 55 3 186 0.4221
Osher-TPQ 5-HTTLPR 44.7027 39 73 36 148 0.8703
Ricketts 5-HTTLPR 38.7027 10 14 13 37 0.185
Samachowiec 5-HTTLPR 43.51351 18 67 41 126 0.356
Schmidt 5-HTTLPR 39.78378 12 29 16 57 1
Sen 5-HTTLPR 59.13514 83 183 149 415 0.0557
Stoltenberg 5-HTTLPR 41.35135 17 45 24 86 0.6704
Strobel 5-HTTLPR 43.35135 22 67 34 123 0.3619
Tsai 5-HTTLPR 47.08108 100 71 21 192 0.1629
Umekage 5-HTTLPR 49.89189 161 70 13 244 0.156
O'Donnell ACE DI 54.48314 492 845 313 1650 0.1486
O'Donnell ACE DI 53.34439 437 719 288 1444 0.8315
Agerholm-Larsen ACE DI 89.81205 2113 4006 1922 8041 0.7849
Barley ACE DI 46.52294 55 109 46 210 0.678
Benetos ACE DI 46.06965 47 56 25 128 0.2764
Berge ACE DI 46.13599 34 77 29 140 0.3092
Busjahn ACE DI 46.13046 33 79 27 139 0.1272
Cambien ACE DI 49.41404 200 390 143 733 0.0632
Castellano ACE DI 46.40685 76 90 23 189 0.7523
Celermajer ACE DI 46.37922 49 89 46 184 0.6599
Friedl ACE DI 45.72692 16 37 13 66 0.4583
Kauma ACE DI 48.20896 148 264 103 515 0.4783
Kiema ACE DI 46.64456 75 115 42 232 0.8941
Kiema ACE DI 46.65561 54 127 53 234 0.239
Ludwig ACE DI 47.58983 117 206 80 403 0.6152
Mattu ACE DI 52.1393 442 556 228 1226 0.025
Puija ACE DI 46.09176 46 70 16 132 0.203
Rigat ACE DI 45.80431 29 37 14 80 0.8164
Tiret ACE DI 46.44555 60 103 33 196 0.3825
Busch ADD1 48.02101 405 76 0 481 0.0608
Clark ADD1 46.77722 162 80 14 256 0.347
Ju ADD1 49.49696 166 357 225 748 0.3028
Manunta ADD1 45.95909 80 26 2 108 1
Morrison ADD1 56.05307 1227 643 64 1934 0.0747
Mulatero ADD1 46.28524 117 43 7 167 0.2699
Narita ADD1 46.88778 56 150 70 276 0.1494
Nicod ADD1 46.79934 167 83 10 260 1
Persu ADD1 46.41791 121 63 7 191 0.8258
Ranade ADD1 51.2272 296 530 235 1061 0.95
Shioji ADD1 67.08184 241 560 305 06 0.428
Yamagishi ADD1 60.96739 599 365 859 2823 0.967
berg bsm1 41.67598 2 9 8 49 0.504
boschitsch bsm1 48.04469 36 67 60 63 0.0539
garnero bsm1 53.906 38 34 96 268 0.523
gennari bsm1 61.84358 7 29 20 40 0.087
gomez bsm1 47.93296 27 72 62 6 0.5075
hansen bsm1 50.11173 46 98 56 200 0.7787
jorgensen bsm1 69.60894 77 276 96 549 0.209
kiel bsm1 45.2514 22 7 74 113 22E-10
kroger bsm1 40.22346 2 4 7 23 0.3787
langdahl bsm1 43.40782 25 34 2 80 0.848
marc bsm1 44.63687 9 59 24 02 0.634
mcclure bsm1 44.69274 8 43 52 03 1
melhus bsm1 43.18436 7 35 34 76 0.7943
riggs bsm1 44.02235 5 36 40 9 0.765
vandevyer bsm1 71.78771 107 306 75 588 0.2098
aerssens COLIA1 50.90116 151 73 5 239 0.295
alvarez COLIA1 44.65116 2 3 0 24 1
de vernejoul COLIA1 47.93605 85 5 1 37 0.0267
efstathiodou COLIA1 47.18023 73 29 9 111 0.043
heegaard COLIA1 47.18023 82 27 2 111 1
hustmyer COLIA1 46.22093 58 6 4 78 0.079
keen COLIA1 47.73256 85 40 5 130 1
langdahl COLIA1 48.13953 94 48 2 44 0.664
liden COLIA1 45.90116 44 20 3 67 0.698
mcguigan COLIA1 46.51163 70 7 1 88 1
roux COLIA1 47.06395 8 24 2 07 1
uitterlinden COLIA1 82.87791 905 392 42 339 1
weichetova COLIA1 47.61628 94 30 2 126 1
bagnoli CTSD 42.01754 1 26 99 126 1
bertram CTSD 46.92982 1 29 152 182 1
bhojak CTSD 58.68421 0 56 260 316 0.151
crawford CTSD 41.49123 0 20 100 120 1
crawford CTSD 40.78947 2 28 82 112 1
emahazion CTSD 44.03509 3 27 119 149 0.3899
ingegni CTSD 41.49123 1 21 98 120 1
mateo CTSD 61.31579 8 54 284 346 0.0143
matsui CTSD 72.98246 1 7 471 479 0.0372
mcilroy CTSD 47.36842 1 16 170 187 0.3491
menzer CTSD 57.4564 1 33 268 302 1
papassotiropoulos CTSD 61.75439 0 47 304 351 0.3847
papassotiropoulos CTSD 47.10526 0 18 166 184 1
prince CTSD 46.22807 0 22 152 174 1
styczynska CTSD 39.73684 0 9 91 100 1
chang CYP17 45.82569 26 79 77 182 0.4248
gsur CYP17 43.25688 12 67 47 126 0.1219
habuchi CYP17 52.75229 69 157 107 333 0.4371
haiman CYP17 73.34862 127 350 305 782 0.1312
kittles CYP17 42.56881 10 46 55 111 1
latil CYP17 44.63303 24 84 48 156 0.2511
lunn CYP17 44.77064 18 73 68 159 0.8621
stanford CYP17 61.46789 79 256 188 523 0.6477
wadelius CYP17 44.81651 26 88 46 160 0.1979
yamada CYP17 46.65138 29 120 51 200 0.004
amadeo drd2 43.48837 0 7 36 43 1
Anghelescu drd2 56.27907 3 32 63 98 1
Bau drd2 60 6 36 72 114 0.5764
blum drd2 39.06977 0 4 20 24 1
blum drd2 40.69767 0 6 25 31 1
bolos drd2 63.02326 8 30 89 127 0.034
comings drd2 58.60465 0 24 84 108 0.3553
cook drd2 38.3953 0 6 4 20 1
geijer drd2 52.32558 5 24 52 8 0.3226
gelernter drd2 49.30233 3 2 44 68 0.7138
goldman drd2 4.86047 2 11 23 36 0.6232
heinz drd2 59.76744 4 35 74 113 1
Hietala drd2 45.11628 0 11 39 50 1
lawford drd2 44.18605 3 11 32 46 0.1562
neiswanger drd2 40.4652 0 4 26 30 1
noble drd2 46.97674 3 4 4 58 0.3437
Ovchiunikov drd2 51.16279 4 23 49 76 0.494
parsian drd2 39.30233 0 3 22 25 1
Pastorelli drd2 48.37209 2 3 49 64 0.2895
Samochoweic drd2 78.3953 5 5 36 92 1
suarez drd2 53.95349 2 23 63 88 1
abbate gpIIIa 43.2963 3 9 5 73 0.4229
aleksic gpIIIa 60.74074 0 4 403 544 0.000039
anderson gpIIIa 50.848 9 65 202 276 0.2337
anderson gpIIIa 46.88889 6 42 22 170 0.3835
ardissino gpIIIa 48 4 33 63 200 0.324
boncler gpIIIa 43.55556 0 9 6 80 0.5896
bottiger gpIIIa 53.18519 9 84 247 340 0.5261
carter gpIIIa 44.81481 0 28 86 114 0.2131
carter gpIIIa 48.59259 3 57 156 216 0.5836
carter gpIIIa 43.92593 2 24 64 90 1
corral gpIIIa 44.33333 0 35 66 101 0.038
durante-mangoni gpIIIa 43.22222 0 9 52 71 0.3451
garcia gpIIIa 44.2963 1 12 87 100 0.3864
gardemann gpIIIa 84.7037 31 297 863 1191 0.3654
grand maison gpIIIa 44.2963 1 23 76 100 1
hermann gpIIIa 47.11111 4 43 129 176 0.7646
hermann gpIIIa 59.96296 10 143 370 523 0.5047
hooper gpIIIa 47.44444 2 39 144 185 1
joven gpIIIa 49.85185 3 85 66 250 0.0483
kekomaki gpIIIa 42.22222 2 7 35 44 0.1123
kekomaki gpIIIa 43.62963 1 17 64 82 1
laule gpIIIa 76.59259 20 254 698 972 0.7073
mamotte gpIIIa 61.7037 12 136 422 570 0.7302
marian gpIIIa 46.66667 7 38 119 64 0.135
moshfegh gpIIIa 43.88889 6 14 69 89 0.0023
osborn gpIIIa 46.77778 8 27 32 67 0.0015
pastinen gpIIIa 46.18519 2 26 123 151 0.6399
ridker gpIIIa 66.66667 22 164 518 704 0.0513
samani gpIIIa 49.2963 5 97 133 235 0.0086
scaglione gpIIIa 44.22222 1 27 70 98 0.6863
senti gpIIIa 45.62963 3 28 105 136 0.4363
weiss gpIIIa 43.11111 1 12 55 68 0.525
zotz gpIIIa 43.96296 0 23 68 91 0.3467
Combarros IL-1 52.10145 195 104 7 306 0.408
Du IL-1 43.76812 126 62 3 191 0.2122
Green IL-1 66.37681 221 27 65 503 0.3238
Grimaldi IL-1 54.2029 142 63 30 335 0.109
Hedley IL-1 55.36232 153 68 30 35 0.113
Ki IL-1 36.66667 72 21 0 93 0.5969
Minster IL-1 46.73913 115 99 18 232 0.75
Nicoll IL-1 42.02899 82 74 11 167 0.3481
Pirskanen IL-1 67.10145 248 209 56 513 0.2582
Rebeck IL-1 43.47826 97 74 16 187 0.7202
Tsai IL-1 42.24638 147 22 1 170 0.5822
chenevix-Trench LmycECOR1 57.46667 46 72 43 161 0.2068
chernitsa LmycECOR1 46.26667 18 38 21 77 1
crossen LmycECOR1 49.33333 43 43 14 100 0.5194
dlugosz LmycECOR1 44.66667 11 38 16 65 0.2145
dolcetti LmycECOR1 46.4 24 35 19 78 0.3718
ejarque LmycECOR1 50.66667 40 45 25 110 0.0825
fernandez LmycECOR1 49.46667 30 49 22 101 0.842
ge LmycECOR1 39.46667 6 12 8 26 0.7061
hseih LmycECOR1 47.73333 22 39 27 88 0.2921
isbir LmycECOR1 47.06667 39 29 15 83 0.0323
isbir LmycECOR1 42.8 23 26 2 51 0.1768
ishizaki LmycECOR1 49.33333 17 63 20 100 0.0157
kato LmycECOR1 49.06667 17 61 20 98 0.0254
kondratieva LmycECOR1 49.6 28 52 22 102 1
kuminoto LmycECOR1 68.13333 59 134 48 241 0.0934
murakami LmycECOR1 79.6 69 183 75 327 0.0358
saranath LmycECOR1 49.46667 30 49 22 101 0.842
shibuta LmycECOR1 50.26667 34 55 18 107 0.6938
shibuta LmycECOR1 50.26667 34 55 18 107 0.6938
shih LmycECOR1 53.33333 43 54 33 130 0.0767
taylor LmycECOR1 46.13333 22 31 23 76 0.1118
tefre LmycECOR1 53.2 35 59 35 129 0.3782
togo LmycECOR1 76.8 85 143 78 306 0.2544
weston LmycECOR1 43.33333 10 22 23 55 0.2616
weston LmycECOR1 40.8 11 17 8 36 0.7464
weston LmycECOR1 37.73333 2 4 7 13 0.5079
yaylim LmycECOR1 40.93333 14 16 7 37 0.5121
young LmycECOR1 42.4 16 29 3 48 0.0606
Adams MTHFR C677T 47.57246 29 97 96 222 0.557
brugada MTHFR C677T 45.14493 12 73 70 155 0.2683
Brulhart MTHFR C677T 56.05072 73 195 188 456 0.0715
Christensen MTHFR C677T 43.91304 13 61 47 121 0.4287
de Franchis MTHFR C677T 48.87681 39 129 90 258 0.6041
Deloughery MTHFR C677T 61.12319 94 262 240 596 0.117
Gallagher MTHFR C677T 43.33333 7 45 53 105 0.6343
Izumi MTHFR C677T 46.81159 25 102 74 201 0.2965
Kluijtmans MTHFR C677T 43.55072 6 42 63 111 1
Kluijtmans MTHFR C677T 84.81884 106 527 617 1250 0.6841
Ma MTHFR C677T 50.03623 39 116 135 290 0.0868
malinow MTHFR C677T 43.22464 8 45 49 102 0.8129
markus MTHFR C677T 45.36232 22 63 76 161 0.1545
morita MTHFR C677T 67.71739 79 361 338 778 0.2587
Narang MTHFR C677T 41.34058 5 19 26 50 0.7298
salden MTHFR C677T 45.47101 18 75 71 164 0.8626
Schmitz MTHFR C677T 46.34058 27 90 71 188 1
Schwartz MTHFR C677T 51.77536 43 141 154 338 0.2251
tosetto MTHFR C677T 44.23913 17 71 42 130 0.1486
van bockxmeer MTHFR C677T 44.71014 15 58 70 143 0.5591
Verhoef MTHFR C677T 43.15217 7 48 45 100 0.3479
verhoef MTHFR C677T 57.64493 72 200 228 500 0.013
Wilcken MTHFR C677T 47.68116 24 113 88 225 0.1929
Awata Neurod1 71.75824 1 55 327 383 0.7094
Cinek Neurod1 61.42857 42 130 117 289 0.5308
Dupont Neurod1 42.1978 18 53 43 114 0.8444
Dupont Neurod1 42.1978 18 53 43 114 0.8444
Hansen Neurod1 58.35165 48 108 105 261 0.0374
Iwata Neurod1 48.79121 0 17 157 174 1
Jackson Neurod1 64.3956 2 73 241 316 0.1963
Kanatsuka Neurod1 49.12088 0 22 155 177 1
Malecki Neurod1 44.94505 14 75 50 139 0.1004
Malecki Neurod1 48.46154 25 68 78 171 0.1277
Mockizuki Neurod1 42.96703 0 12 109 121 1
Owerback Neurod1 38.46154 10 36 34 80 1
Yamada Neurod1 43.07692 4 33 85 122 0.7447
Ye Neurod1 43.2967 0 3 111 124 1
antikainen PON1 Q192R 45.24735 87 75 7 169 0.0753
aubo PON1 Q192R 47.73852 154 23 33 30 0.2833
aynacioglu PON1 Q192R 44.11661 11 43 5 05 0.652
ayub PON1 Q192R 43.14488 32 5 3 50 0.4242
cascorbi PON1 Q192R 59.62898 521 39 7 983 0.872
chen PON1 Q192R 49.52297 208 66 37 411 0.634
ferre PON1 Q192R 46.06007 106 93 6 25 0.692
gardemann PON1 Q192R 51.71378 279 26 40 535 0.94
hasselwander PON1 Q192R 49.11661 179 78 3 388 0.1905
heijman PON1 Q192R 52.93286 291 263 50 604 0.4386
hermann PON1 Q192R 54.64664 362 265 74 70 0.08
hong PON1 Q192R 45.63604 75 84 32 191 0.3597
imai PON1 Q192R 49.87633 59 82 90 431 0.1672
ko PON1 Q192R 46.11307 30 96 92 28 0.5562
lawlor PON1 Q192R 91.4841 1430 1115 24 2786 0.2662
letellier PON1 Q192R 43.9576 55 38 3 96 0.3843
leus PON1 Q192R 44.27562 56 48 0 114 1
liu PON1 Q192R 44.52297 25 74 29 128 0.1104
mackness PON1 Q192R 47.24382 156 99 27 282 0.0698
odawara PON1 Q192R 44.41696 25 53 44 22 0.2648
ombres PON1 Q192R 45.86572 06 84 4 204 0.7264
osei-hyiaman PON1 Q192R 46.34276 8 44 6 23 0.1172
pati PON1 Q192R 43.67491 60 2 8 80 0.000
pfohl PON1 Q192R 45.26502 73 77 20 170 1
rice PON1 Q192R 52.98587 312 24 54 607 0.4298
robertson PON1 Q192R 85.08834 37 90 97 2424 0.0263
ruiz PON1 Q192R 46.90813 40 110 3 263 0.1968
salonen PON1 Q192R 44.18728 59 43 7 09 1
sangera PON1 Q192R 46.57244 4 23 80 244 0.6933
sangera PON1 Q192R 45.17668 77 66 22 65 0.299
sen-banerjee PON1 Q192R 51.41343 279 226 13 518 0.000013
senti PON1 Q192R 49.25795 193 65 38 396 0.7234
serrato PON1 Q192R 46.62544 120 99 28 247 0.3007
suehiro PON1 Q192R 46.71378 34 24 94 252 0.5929
tuban PON1 Q192R 47.57951 136 43 22 30 0.0794
wang PON1 Q192R 50.65371 193 230 52 475 0.1919
watzinger PON1 Q192R 46.85512 147 96 7 260 0.8684
yamada PON1 Q192R 62.89753 523 56 29 68 0.9473
zama PON1 Q192R 44.29329 17 6 37 115 0.4408
Febbo SRD5A2 73.11111 78 330 39 799 0.5038
Hsing SRD5A2 51.06667 105 36 62 303 0.159
Latil SRD5A2 44.53333 8 64 84 56 0.4069
Lunn SRD5A2 44.17778 13 58 77 148 0.6865
Lunn SRD5A2 37.95556 1 5 2 8 1
Margiotti SRD5A2 42.75556 9 40 67 116 0.4555
Nam SRD5A2 44.8 21 69 72 62 0.488
Pearce SRD5A2 64.26667 76 263 26 600 0.4703
Pearce SRD5A2 50.22222 43 56 85 284 0.058
Pearce SRD5A2 55.86667 21 159 23 411 0.4226
Soderstrom SRD5A2 44.66667 16 66 77 159 0.728
Yamada SRD5A2 46.62222 50 97 56 203 0.5742
abbar TPH 58.38095 30 33 118 28 0.5079
bellivier TPH 40.57143 11 45 38 94 0.8226
du TPH 39.61905 13 52 9 84 0.047
furlong TPH 73.2381 67 208 62 437 1
geijer TPH 40.95238 13 47 38 98 1
kunugi TPH 51.52381 55 05 49 209 1
ono TPH 44.19048 26 7 35 32 0.3875
paik TPH 54.09524 66 116 54 236 0.896
rujescu TPH 62.66667 40 55 3 326 0.635
souery TPH 47.52381 27 74 66 67 0.46
tsai TPH 50.66667 33 113 54 200 0.0624
turecki TPH 43.90476 18 7 40 129 0.1507
zaisman TPH 42.28571 34 54 24 112 0.8488
Blazer VDR Taq1 50.06579 35 74 59 68 0.2079
Blazer VDR Taq1 39.93421 3 2 9 4 0.026
Correa-Cerro VDR Taq1 45.26316 11 52 32 95 0.1957
Furuya VDR Taq1 42.96053 1 8 4 60 1
Gsur VDR Taq1 51.51316 22 87 8 90 1
Habuchi VDR Taq1 61.18421 3 8 253 337 0.3282
Hamasaki VDR Taq1 47.76316 8 34 9 33 0.0823
Kibel VDR Taq1 41.31579 7 5 3 35 0.4978
Kibel VDR Taq1 39.40789 1 3 2 6 1
Luscombe VDR Taq1 49.14474 30 67 57 154 0.2436
Ma VDR Taq1 77.76316 86 299 204 589 0.1706
Medeiros VDR Taq1 52.56579 4 92 73 206 0.2529
Suzuki VDR Taq1 45.92105 2 20 83 05 0.684
Tayeb VDR Taq1 63.94737 62 8 36 379 0.95
Taylor VDR Taq1 49.67105 36 73 53 62 0.2677
Taylor VDR Taq1 39.53947 1 6 1 8 0.4779
Watanabe VDR Taq1 52.30263 6 36 60 202 0.042