Table 2.
Frequencies of eNOS -786T > C and 894G > T genotypes and alleles in CABG patients and control subjects
| eNOS | CABG patients (n = 154) |
Controls (n = 155) |
p value |
||
|---|---|---|---|---|---|
|
n (%) |
95% CI |
n (%) |
95% CI |
||
| -786T > C genotypes | |||||
| TT | 43 (27.9) | 21.3-35.4 | 39 (25.2) | 18.8-32.4 | 0.73 |
| TC | 85 (55.2) | 47.3-62.9 | 85 (54.8) | 46.9-62.5 | |
| CC | 26 (16.9) | 11.6-23.4 | 31 (20.0) | 14.3-26.8 | |
| -786T > C alleles |
n = 308 | n = 310 | |||
| T | 171 (55.5) | 49.9-61.0 | 163 (52.6) | 47.0-58.1 | 0.46 |
| C | 137 (44.5) | 39.0-50.1 | 147 (47.4) | 41.9-52.9 | |
| 894G > T genotypes | |||||
| GG | 74 (48.1) | 40.3-55.9 | 72 (46.5) | 38.7-54.3 | 0.95 |
| GT | 63 (40.9) | 33.4-48.8 | 66 (42.5) | 34.9-50.4 | |
| TT | 17 (11.0) | 6.8-16.7 | 17 (11.0) | 6.8-16.6 | |
| 894G > T Alleles | n = 308 | n = 310 | |||
| G | 211 (68.5) | 63.2-73.5 | 210 (67.7) | 62.4-72.8 | 0.84 |
| T | 97 (31.5) | 26.5-36.8 | 100 (32.3) | 27.2-37.6 | |
Frequencies of all genotypes and alleles are in Hardy-Weinberg equilibrium.
Genotype and allele frequencies between the two groups were analysed by the chi-square test.
Abbreviations: CABG, coronary artery bypass graft; CI, confidence interval.