Table 1.

Patient demographics and clinical characteristics at baseline

Abbreviations: CI = confidence interval; CIS:MS = ratio of patients with optic neuritis as a clinically isolated syndrome vs relapsing-remitting multiple sclerosis; DMT = patients with relapsing-remitting multiple sclerosis or CIS using disease-modifying drug therapy (interferon or glatiramer acetate) at time of acute optic neuritis event; EDSS = Expanded Disability Status Scale; MRI (%) = patients with evidence of disseminated CNS inflammation³⁵ on baseline MRI; OD = right eye; OS = left eye; OU = both eyes.

^aUnpaired Student t test.

^bχ² test.

^cc Fisher exact test.

^dWilcoxon rank sum test.

^eMean duration³⁴ for the diagnosis of relapsing-remitting multiple sclerosis or CIS.

^fPatients treated with high-dose corticosteroid therapy for acute ON (equivalent to 1,000 mg methylprednisolone daily for 5 days) initiated within the first 2 weeks of therapy.